%0 Journal Article
%T 白芍药材及其配方颗粒的UPLC指纹图谱研究<br>Study on UPLC Fingerprint of <i>Paeonia lactiflora</i> Pall. and Its Formula Granules
%A 刘红云
%A 杨小松
%A 吴红梅
%A 王祥培
%J Pharmacy Information
%P 300-308
%@ 2160-4452
%D 2023
%I Hans Publishing
%R 10.12677/PI.2023.124038
%X <span style=\"font-size:14px;\">目的：建立白芍药材及其配方颗粒的UPLC指纹图谱。方法：色谱柱为ACQUITY UPLC BEH C18 (2.1 mm × 100 mm, 1.7 μm)，以0.05%磷酸水溶液–乙腈为流动相，梯度洗脱，流速为0.1 mL/min；检测波长为254 nm；柱温为30℃；采用中药色谱指纹图谱评价系统进行相似度分析。结果：20批白芍药材及其配方颗粒的UPLC指纹图谱共确认11个共有峰，并指认出芍药苷和没食子酸两种化学成分。结论：该方法准确、可行、重现性好，反映白芍药材及配方颗粒多成分的整体面貌，可为白芍药材及其配方颗粒质量评价提供参考。</span><br />
<span style=\"font-size:14px;\">Objective: To establish the UPLC fingerprint of Paeonia lactiflora Pall. and its formula granules. Methods: The chromatographic column is ACQUITY UPLC BEH C18 (2.1 mm × 100 mm, 1.7 μm) with acetonitrile-0.05% phosphoric acid aqueous solution as the mobile phase in a gradient mode at the flow rate of 0.1 mL/min. The detection wavelength is 254 nm and the column temperature is 30？C. The similarity is evaluated using a traditional Chinese medicine chromatographic fingerprint eval-uation system. Results: A total of 11 common peaks were identified in the UPLC fingerprint of 20 batches of Paeonia lactiflora Pall. and their formula granules, and two chemical components, pae-oniflorin and gallic acid, were identified. Conclusion: This method is accurate, feasible, and has good reproducibility, reflecting the overall appearance of multiple components in Paeonia lactiflora Pall. and its formula granules. It can provide a reference for the quality evaluation of the Paeonia lactiflora Pall. and its formula granules.</span>
%K 白芍，UPLC指纹图谱，配方颗粒<br><i>Paeonia lactiflora</i> Pall.
%K UPLC Fingerprint
%K Formula Granules
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=68602