%0 Journal Article
%T Copper-Catalyzed C-C(O)C Bond Cleavage of Monoalkylated <i>¦Â</i>-Diketone: Synthesis of <i>¦Á</i>,<i>¦Â</i>-Unsaturated Ketones
%A Tony Wheellyam Pouambeka
%A Victor N¡¯goka
%A Narcisse Nicaise Obaya
%A Guy Cr¨¦pin Enoua
%A Hubert Makomo
%A Qian Zhan
%J International Journal of Organic Chemistry
%P 41-49
%@ 2161-4695
%D 2023
%I Scientific Research Publishing
%R 10.4236/ijoc.2023.132004
%X A new and simple route for the synthesis of <i>¦Á</i>,<i>¦Â</i>-unsaturated ketones via cleavage of the C-C(O)C single bond of monoalkylated <i>¦Â</i>-diketone has been described. The reaction was catalyzed by copper, a cheap transition metal in a weakly basic medium (K<sub>3</sub>PO<sub>4</sub>) at room temperature. To carry out this study, we first had to synthesize the monoalkylated <i>¦Â</i>-diketones 1. Afterwards, <i>¦Á</i>,<i>¦Â</i>-unsaturated ketones 2 were obtained with high yields around 80%. Finally, all the products were characterized by 1H NMR, 13C NMR, and HRMS spectra.
%K Monoalkylated &lt
%K i&gt
%K ¦Â&lt
%K /i&gt
%K -diketone
%K &lt
%K i&gt
%K ¦Á&lt
%K /i&gt
%K &lt
%K i&gt
%K ¦Â&lt
%K /i&gt
%K -Unsaturated Ketones
%K Copper-Catalyzed
%K C-C(O)C Bond Cleavage
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=125563