%0 Journal Article
%T Preparation and properties of microporous scaffolds by 3D printing of bio-based polylactic acid composites
%A QIN Liuqi
%A DONG Xianming
%A SU Xiangyu
%A ZHOU Wuyi
%A ZHENG Wenxu
%J Journal of South China Agricultural University
%R 10.7671/j.issn.1001-411X.202106012
%X ¡¾Objective¡¿ To explore the feasibility of using bio-based polylactic acid composites to directly construct microporous scaffolds by 3D printing.¡¾Method¡¿ Thermogravimetric analyzer and differential scanning calorimeter were used to explore the thermal properties of bio-based polylactic acid composites, scanning electron microscopy was used to characterize the microscopic morphology of the bio-scaffold, and the live/dead cell staining was used for detecting cell adhesion of the scaffold.¡¾Result¡¿ The prepared 0.6%ADC-PHAP and 40%NaCl-PHAP composites had good thermal stability and processability, and were suitable for the fused deposition modeling 3D printing process. When the compressive strain was 80%, the corresponding compressive stresses of the 0.6%ADC-PHAP and 40%NaCl-PHAP scaffolds were 45.27 and 52.11 MPa, respectively. The initial decomposition temperature of the 0.6%ADC-PHAP composite was 19.5 ¡æ lower than that of the 40%NaCl-PHAP composite. The porosity of the 0.6%ADC-PHAP scaffold reached 63.33% which was conducive to cell adhesion, and the cell compatibility was better than that of the 40%NaCl-PHAP scaffold.¡¾Conclusion¡¿ The bio-based polylactic acid composites can be used to directly construct microporous bio-scaffolds through fused deposition modeling 3D printing, and the prepared 0.6%ADC-PHAP bio-scaffold has certain application potential.
%K Melt blending
%K 3D printing
%K Scaffold
%K Polylactic acid
%K Bio-based material
%U https://xuebao.scau.edu.cn/zr/html/2022/1/20220105.htm