%0 Journal Article
%T Late Onset Combined Immune Deficiency (LOCID) Revealed by a Haemolytic Anaemia in a Child: A Case Report
%A Amal Hamami
%A Maria Rkain
%A Madiha Benhachem
%A Ayyad Ghannam
%A Aziza Elouali
%A Abdeladim Babakhoua
%A Noufissa Benajiba
%J Open Journal of Pediatrics
%P 347-351
%@ 2160-8776
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojped.2023.133040
%X Variable
Common Immune Deficiency (VCID) is a very heterogeneous condition both
clinically and immunologically. It is a group of molecular abnorm</span><span style=\"font-family:Verdana;\">alities responsible for a defect in antibody
production leading to hyp</span><span style=\"font-family:Verdana;\">ogammaglobulinemia often associated with
autoimmune and/or lymphoproliferative manifestations.</span></span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">Late Onset Combined Immune Deficiency (LOCID) is a
type of Variable Common Immune Deficiency (VCID) defined by a defect in
antibody production (IgG and IgA </span><span style=\"font-family:Verdana;\">¡À</span><span style=\"font-family:Verdana;\"> IgM
type), profound CD4 T-cell lymphopenia and frequent opportunistic infections.</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">LOCID has been considered as
a distinct entity from VCID due to its particular clinical and immunological
profile.
%K Haemolytic Anaemia
%K LOCID
%K Immune Deficiency
%K Child
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=124865