%0 Journal Article
%T Functional Genes in Relation to Residual Feed Intake in Murrah Buffalo Heifers
%A Poonam Sikka
%A Shyam Sunder Paul
%A Andonissamy Jerome
%A Dwijesh Mishra
%A Krishna Kumar Chaturvedi
%A Inderjeet Singh
%A Anil Rai
%J Advances in Bioscience and Biotechnology
%P 210-236
%@ 2156-8502
%D 2023
%I Scientific Research Publishing
%R 10.4236/abb.2023.144014
%X High Feed efficiency (FE) in growing heifers has economic importance in dairy,
but remains less understood in buffaloes. Feed conversion efficiency is defined
as dry matter intake (DMI) per unit body weight gain and is determined as
residual feed intake (RFI), <i>i.e</i>.<span style=\"font-family:;\" \"=\"\">, the </span><span style=\"font-family:;\" \"=\"\">difference between actual and predicted feed intake
to gain unit body weight during a feed trial run for 78 days under control
feeding. A large variation was identified ranging between -0.42 to 0.35 in
growing buffalo heifers (n</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">=</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">40) </span><span style=\"font-family:;\" \"=\"\">of </span><span style=\"font-family:;\" \"=\"\">age
between 11 to 15 months. An average daily weight gain (ADG) varied between
382.0 and 807.6 g/day wh</span><span style=\"font-family:;\" \"=\"\">en</span><span style=\"font-family:;\" \"=\"\"> compar</span><span style=\"font-family:;\" \"=\"\">ed</span><span style=\"font-family:;\" \"=\"\"> with the control-fed heifers at </span><span style=\"font-family:;\" \"=\"\">an </span><span style=\"font-family:;\" \"=\"\">organized buffalo farm. </span><span style=\"font-family:;\" \"=\"\">The whole blood transcriptome data obtained from the
selected growing heifers from extremes of estimated high and low RFI efficiency
were compared with the reference assembly generated from the transcriptome of
multiparous buffaloes (n = 16) of diverse age of maturity, period of regaining
post partum cyclicity and level of milk production</span><span style=\"font-family:;\" \"=\"\">.
Differentially expressed genes (DEGs) were identified using </span><span style=\"font-family:;\" \"=\"\">the </span><span style=\"font-family:;\" \"=\"\">reference genome of Mediterranean water buffalo. GO:
terms (Padj</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">&lt;</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">0.05, FDR</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">&lt;</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">0.05)
enriched by annotated DEGs and biological pathways in gene network for RFI
efficiency trait were identified. GO:</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\">terms
specific to pre-transcriptional
%K &lt
%K i&gt
%K Bubalus bubalis&lt
%K /i&gt
%K Feed Efficiency
%K Residual Feed Intake
%K Blood Transcriptome
%K Differentially Expressed Genes
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=124682