%0 Journal Article
%T IVF-ET拮抗剂方案黄体支持研究进展<br>Clinical Research Progress on Luteal Phase Support of Antagonist in IVF-ET
%A 陈琰睿
%A 师娟子
%A 李娜
%J Advances in Clinical Medicine
%P 5215-5222
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.134738
%X 随着辅助生殖技术(assisted reproductive technology, ART)的发展，促性腺激素释放激素拮抗剂(gonadotropin releasing hormone antagonist, GnRH-A)方案被广泛应用于临床中，逐渐成为主流方案之一。拮抗机方案起效快、副作用少、可降低卵巢过度刺激综合征(Ovarian hyperstimulation syn-drome, OHSS)发生率及无“点火”效应等优点。但拮抗剂方案可能存在的溶黄体作用及取卵术后颗粒细胞丢失等因素会导致IVF-ET后黄体功能不足。故在拮抗剂方案中黄体支持的选择尤为重要。本文主要对在促性腺激素释放激素拮抗剂方案中黄体支持进行文献回顾及综述。<br />
With the development of assisted reproductive technology (ART), gonadotropin releasing hormone antagonist (GnRH-A) regimen has been widely used in clinical practice and gradually becomes one of the mainstream programs. The antagonist regimen has the advantages of start fast, less side ef-fect, reduced incidence of Ovarian hyperstimulation syndrome (OHSS), and no “flareup” effect. However, factors such as possible luteolytic effect of antagonist regimens and loss of granulosa cells after oocyte retrieval can lead to the defects of luteal function after IVF-ET. Therefore, the choice of luteal phase support in antagonist regimens is particularly important. This article mainly reviews the luteal support in gonadotropin-releasing hormone antagonist regimens.
%K 促性腺激素释放激素拮抗剂，黄体支持，孕酮<br>Gonadotropin Releasing Hormone Antagonist
%K Luteal Phase Support
%K Progesterone
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=63714