%0 Journal Article
%T 长链非编码RNA对心脏成纤维细胞功能的研究进展<br>Advances in the Study of Long Non-Coding RNA on Cardiac Fibroblast Function
%A 孔开元
%A 陈雪英
%A 刘立新
%J Advances in Clinical Medicine
%P 3184-3193
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.133453
%X 心脏成纤维细胞参与心脏各种损伤的修复，可以维持心脏结构和功能的完整。非编码RNA参与许多疾病的进展，已经成为进一步了解成纤维细胞的新方向，其中长链非编码RNAs (Long Non-Coding RNAs, LncRNAs)数量丰富、种类众多，本文总结通过调控心脏成纤维细胞参与心脏重构的长链非编码RNAs，并简述其作用机制。<br />
Cardiac fibroblasts are involved in the repair of various cardiac injuries and can maintain the structural and functional integrity of the heart. The involvement of non-coding RNA in the pro-gression of many diseases has become a new direction for further understanding of fibroblasts, among which long non-coding RNAs (LncRNAs) are abundant and diverse. In this paper, we sum-marize the long non-coding RNAs involved in cardiac remodeling through regulation of cardiac fi-broblasts, and briefly describe their mechanisms of action.
%K 长链非编码RNA，心脏成纤维细胞，心脏重构<br>Long Non-Coding RNA
%K Cardiac Fibroblasts
%K Cardiac Remodeling
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=62324