%0 Journal Article
%T 幽门螺杆菌感染与结直肠肿瘤的相关性研究进展<br>Research Progress of Correlation between Helicobacter pylori Infection and Colorectal Neoplasms
%A 付立群
%A 于佳琪
%A 营浩东
%A 张庆龙
%A 王延淼
%A 赵健翔
%A 高玉强
%J Advances in Clinical Medicine
%P 3131-3138
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.133445
%X 近年来，越来越多的学者发现幽门螺杆菌感染与胃外疾病密切相关，其中和结直肠肿瘤的相关性成为研究热点。目前研究指出，幽门螺杆菌可通过促进胃泌素分泌、上调环氧合酶-2表达、诱发机体炎性反应、致肠道菌群紊乱等途径参与结直肠肿瘤的发生发展。本文对幽门螺杆菌感染参与诱发结直肠肿瘤的机制作一综述。<br />
In recent years, more and more scholars have found that Helicobacter pylori infection is closely re-lated to extragastric diseases, and the correlation with colorectal neoplasms has become a research hotspot. Current studies have pointed out that Helicobacter pylori can participate in the occurrence and development of colorectal neoplasms by promoting gastrin secretion, upregulating cyclooxy-genase-2 expression, inducing inflammatory response, and causing intestinal flora disorders. This article reviews the mechanisms that Helicobacter pylori infection is involved in inducing colorectal neoplasms.
%K 结直肠肿瘤，幽门螺杆菌，致病机制<br>Colorectal Neoplasms
%K Helicobacter pylori
%K Pathogenesis
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=62261