%0 Journal Article
%T Congenital Chylothorax Treated with Oral Sildenafil¡ªCase Report from Nigeria and Review of Literature
%A Chinyere C. Uzodimma
%A Saheed B. Sanni
%A Deborah A. Madise-Wobo
%A Charles C. Uzodimma
%J Open Journal of Pediatrics
%P 189-195
%@ 2160-8776
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojped.2023.132024
%X Congenital chylothorax, a
condition in which chyle accumulates in the pleural cavity, is extremely rare. The
reported incidence is 1 in 24,000 births. Medical treatment using octreotide as
well as chemical and surgical pleurodesis has been reported, but also few reports on the
successful use of Sildenafil exists. We herein report a case of congenital chylothorax referred to our
Hospital at 7 days-old.
Sildenafil was introduced on day 6 post intubation. Before the introduction of
sildenafil, the peak total daily drainage was 106 ml/kg/day (340 mls/day), and after sildenafil was introduced, the
total daily drainage dropped progressively to 10 ml/kg/day by day 11 post intubation. This case
report highlights the successful use of oral Sildenafil for treatment of
congenital chylothorax and also peculiarities of management related to a
resource- constrained
developing country setting in Africa.
%K Chylothorax
%K Congenital
%K Sildenafil
%K Children
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=123535