%0 Journal Article
%T miRNA在胃癌及结直肠癌中的研究进展
Research Progress of miRNA in Gastric Cancer and Colorectal Cancer
%A 马海明
%A 马新福
%J Advances in Clinical Medicine
%P 2866-2872
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.132405
%X 微小核糖核酸是小的非编码核糖核酸。它们可以调节靶基因的表达,因此,它们的失调显著促进了癌症的发展。越来越多的证据表明,miRNAs可以用作癌症生物标志物。miRNA作为诊断和预后生物标志物的作用及其治疗应用已被广泛研究。本文就miRNA在胃癌及结直肠癌中促癌机制的研究进展作一综述。
MicroRNA is a small noncoding RNA. They can regulate the expression of target genes, so their dis-order significantly promotes the development of cancer. More and more evidence shows that miR-NAs can be used as cancer biomarkers. The role of miRNA as a biomarker for diagnosis and progno-sis and its therapeutic application have been widely studied. In this paper, the research progress of miRNA in promoting cancer in gastric cancer and colorectal cancer is reviewed.
%K miR-21,癌症,胰腺,肝脏,胃肠道,消化系统
MiR-21
%K Cancer
%K Pancreas
%K Liver
%K Gastrointestinal Tract
%K Digestive System
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=61989