%0 Journal Article
%T HCM合并PH的发病机制研究进展<br>Progress in the Pathogenesis of HCM Complicated with PH
%A 娜孜拉·努尔兰
%A 迪丽努尔买买提依明
%J Advances in Clinical Medicine
%P 1805-1811
%@ 2161-8720
%D 2023
%I Hans Publishing
%R 10.12677/ACM.2023.132250
%X 肺动脉高压(Pulmonary hypertension, PH)是一种以肺血管系统为核心的病理综合征，而肥厚型心肌病(Hypertrophic cardiomyopathy, HCM)是最常见的遗传性心肌病之一。HCM患者出现PH后，可能使患者进展为晚期心衰，严重影响HCM患者的生命质量及预后。但近年来HCM相关的PH并未被作为热点进行研究。本文就肺血管阻力、肺血管重构两个方面对HCM患者发生PH的发病机制进行综述。<br />
Pulmonary hypertension (PH) is a pathological syndrome with the pulmonary vasculature system as the core, and hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiomy-opathies. After the occurrence of PH in HCM patients, patients may progress to advanced heart fail-ure, which seriously affects the quality of life and prognosis of HCM patients. However, HCM related PH has not been studied as a hot spot in recent years. This article reviews the pathogenesis of PH in HCM patients from two aspects: pulmonary vascular resistance and pulmonary vascular remodel-ing.
%K 肺动脉高压，肥厚型心肌病，肺血管<br>Pulmonary Hypertension
%K Hypertrophic Cardiomyopathy
%K Pulmonary Vessels
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=61327