%0 Journal Article
%T Predictive Factors of No Reflow during  Primary Angioplasty
%A Mouhaman-Inouwa Kpelafia
%A Ikram Chamtouri
%A Abdou Razak Moukaila
%A Ben Hamda Khaldoun
%A Walid Jomaa
%A Faouzi Maatouk
%J World Journal of Cardiovascular Diseases
%P 32-45
%@ 2164-5337
%D 2023
%I Scientific Research Publishing
%R 10.4236/wjcd.2023.131004
%X <strong>Introduction</strong><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\">: No reflow during primary angioplasty is associated with a poor prognosis despite the reopening of the culprit coronary. The aim of our work </span></span><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\">was to determine the predictive factors of no</span></span><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\"> </span></span><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\">reflow. <b>Methodology</b>: Sin</span></span><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\">gle-center retrospective analytical study from June 2000 to December 2016 that included patients presenting with STEMI took care of by primary angioplasty. No reflow was defined according to angiographic criteria: a TIMI flow &lt; 3 (regardless of the Myocardial Blush Grade) or TIMI flow at 3 with MBG ¡Ü 1, patients were divided into two groups, one group with no reflow and a second group without no reflow. Clinical and angiographic data were compared between the two groups. Univariate and multivariate analysis was performed to determine the predictors of no reflow. <b>Results</b>: The prevalence&nbsp;of no reflow was 24%. In univariate analysis mean age, diabetes,hypertension, tachycardia, hypotension, killip stage 4 left ventricular failure, hyperglycemia &gt; 11, renal failure, left ventricular dysfunction, tritruncal status, common trunk involvement, initial TIMI flow at 0, significant thrombotic load, delay to angioplasty &gt; 6 hours, and predilation were all correlated with no reflow with a p &lt; 0. 05. In multivariate analysis age &gt; 75 years [OR = 6.02, 95% CI 1.4 - 27, p = 0.014], tachycardia [OR = 4.3, 95% CI 1.6 - 7.4, p = 0.037], delay to angioplasty &gt; 6 hours [OR = 1.3, 95% CI 1.1 - 2.1, p = 0.003] and high thrombotic load [OR = 1.5, 95% CI 1.3 - 3.2, p = 0.02] <a name=\"_Hlk124109415\"></a>were independent predictors of no reflow. <b>Conclusion</b>: No reflow is associated with a poor short-</span></span><span style=\"white-space:normal;\"><span style=\"font-family:;\" \"=\"\">term prognosis. Its care requires knowledge of predictive factors, prevention and treatment.</span></span>
%K No Reflow
%K Primary Angioplasty
%K STEMI
%K Thrombus
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=122701