%0 Journal Article %T Drug Resistance in Malaria Parasites: Does ˇ°Specific Antidrug Substanceˇ± Exist? %A Gao-De Li %J Open Access Library Journal %V 10 %N 1 %P 1-6 %@ 2333-9721 %D 2023 %I Open Access Library %R 10.4236/oalib.1109691 %X Development of drug-resistant lines in rodent malaria parasites left us a deep impression on antidrug specificity of antimalarial drug-resistant lines, which is similar to antigen-induced antibody. Based on this comparison, ˇ°specific antidrug substanceˇ± was proposed to explain antidrug specificity of drug-resistant lines. If ˇ°specific antidrug substanceˇ± refers to a protein that is quite like antibody, the concept of ˇ°specific antidrug substanceˇ± is wrong because no such protein has been discovered. However, if ˇ°specific antidrug substanceˇ± refers to a ˇ°specific antidrug group of protein combinationsˇ±, the concept of ˇ°specific antidrug substanceˇ± might be true. A detailed explanation of ˇ°specific antidrug substanceˇ± is presented in this paper. %K Molecular Pharmacology %K Drug Resistance in Malaria Parasite %K ˇ°Specific Antidrug Substanceˇ± %K 3D Genome Architecture %K ˇ°Specific Antidrug Group of Protein Combinationsˇ± %U http://www.oalib.com/paper/6787910