%0 Journal Article
%T 革兰氏阳性菌耐药性的研究进展<br>Research Progress of Drug Resistance in Gram-Positive Bacteria
%A 李彤彤
%A 阮奔放
%J Advances in Microbiology
%P 196-203
%@ 2327-0829
%D 2022
%I Hans Publishing
%R 10.12677/AMB.2022.114025
%X 抗生素的发现为治疗感染性疾病创造了一个转折点，但抗生素在发挥治疗作用的同时，也会诱导细菌耐药性的产生。耐药细菌的出现给利用现有抗生素治疗细菌感染带来了巨大挑战。其中包括很多耐药革兰氏阳性菌，他们给医院感染防控和治疗带来了严重威胁，而耐甲氧西林金黄色葡萄球菌、耐万古霉素屎肠球菌和耐药肺炎链球菌尤其值得关注。在本文中，主要对常见的革兰氏阳性菌耐药机制进行综述。<br />
The discovery of antibiotics has created a turning point for the treatment of infectious diseases, but antibiotics can also induce the development of bacterial resistance while playing a therapeutic role. The emergence of drug-resistant bacteria poses a great challenge to the use of existing antibiotics to treat bacterial infections. These include many drug-resistant Gram-positive bacteria, which pose a serious threat to the prevention and treatment of nosocomial infections. Methicillin- resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and drug-resistant Streptococcus pneumoniae are of particular concern. In this article, the common drug resistance mechanisms of Gram-positive bacteria were reviewed.
%K 抗生素，耐药性，革兰氏阳性菌<br>Antibiotics
%K Drug Resistance
%K Gram-Positive Bacteria
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=58702