%0 Journal Article
%T 稀土配合物生物活性的研究进展
Progress in Bioactivity of Lanthanide Complexes
%A 谢雨甜
%A 王金
%J Journal of Advances in Physical Chemistry
%P 173-184
%@ 2168-6130
%D 2022
%I Hans Publishing
%R 10.12677/JAPC.2022.114020
%X 稀土金属离子具有独特的构造和生理活性,受到研究工作者的广泛重视。稀土离子与有机配体在一定条件下能够生成稀土配合物,生成的配合物大都兼具稀土与配体的功能。将稀土与具有抑菌、抗病毒、抗肿瘤等活性的配体进行配位结合,形成的稀土配合物具有更好的稳定性、适应性以及活性,在研发高效低毒的抗菌、抗病毒、抗肿瘤药物方面具有很高的应用价值。文中介绍了稀土配合物的种类,综述了稀土配合物在抑菌、抗癌等方面的研究进展,指出稀土及其配合物在生物医药领域具有十分广阔的应用前景。
Lanthanide ions have been paid much attention by researchers because of their unique structural and physiological activities. Lanthanide complexes can be formed with rare earth ions and organic ligands under certain conditions, and most of the resulting complexes have both rare earth and ligand functions. By combining lanthanide ions with ligands with antibacterial, antiviral and anti-tumor activities, the lanthanide complexes formed have better stability, adaptability and activity, and have high application value in the research and development of antibacterial, antiviral and anti-tumor drugs with high efficiency and low toxicity. In this paper, the types of lanthanide complexes are introduced, and the research progress of rare earth complexes in bacteriostasis and anticancer is reviewed. It is pointed out that lanthanide ions and its complexes have a very broad application prospect in the field of biomedicine.
%K 稀土,配合物,结构,生物活性
Lanthanide
%K Coordination Compounds
%K Structure
%K Bioactivity
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=57588