%0 Journal Article
%T 放化疗对行胰腺癌根治手术患者预后的影响——基于SEER数据库分析<br>Effects of Radiotherapy and Chemotherapy on Postoperative Prognosis of Patients Undergoing Radical Surgery for Pancreatic Cancer—Based on SEER Database Analysis
%A 苏媛媛
%A 路宁
%A 李茜
%A 温华
%A 张晓庆
%A 马培晗
%A 张明鑫
%J Advances in Clinical Medicine
%P 9540-9550
%@ 2161-8720
%D 2022
%I Hans Publishing
%R 10.12677/ACM.2022.12101380
%X 目的：探究行胰腺癌根治手术患者放化疗对患者预后的影响。方法：选取SEER数据库中2010年到2015年行根治手术治疗的胰腺癌患者，采用COX比例风险模型、χ2和Kaplan-Meier法，进行分析。结果：年龄是影响胰腺癌患者术后的独立影响因素，中青年患者预后较老年患者好，但无论在老年组还是中青组，对于临床分期和TNM分期较差的患者，放疗和化疗可以改善患者的预后。但对分化程度、临床分期和TNM分期较好的患者，化疗和放疗可能不利于其预后。结论：对于临床分期和TNM分期差的行根治手术患者，放疗和化疗能显著改善其预后，使其生存周期延长。<br />
Objective: To investigate the effect of radiotherapy and chemotherapy on prognosis of patients un-dergoing radical surgery for pancreatic cancer. Methods: Patients with pancreatic cancer who un-derwent radical surgery from 2010 to 2015 were selected from the SEER database and analyzed by COX proportional risk model, χ2 and Kaplan-Meier. Result: Age is an independent factor affecting postoperative pancreatic cancer patients, and the prognosis of young and middle-aged patients is better than elderly patients, but whether in the elderly group or the middle-aged group, radio-therapy and chemotherapy can improve the prognosis of patients with poor clinical stage and TNM stage. However, chemotherapy and radiotherapy may be detrimental to the prognosis of patients with better differentiation, clinical stage and TNM stage. Conclusion: For patients with poor clinical stage and TNM stage, radiotherapy and chemotherapy can significantly improve their prognosis and prolong their survival cycle.
%K 胰腺癌，根治手术，预后，放化疗<br>Pancreatic Cancer
%K Radical Surgery
%K Prognosis
%K Radiotherapy and Chemotherapy
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=57103