%0 Journal Article
%T PD-L1检测方法及研究进展<br>PD-L1 Detection Methods and Research Progress
%A 王皓
%A 陈宗友
%A 刘一雄
%J Medical Diagnosis
%P 265-270
%@ 2164-5418
%D 2022
%I Hans Publishing
%R 10.12677/MD.2022.123043
%X 近年来，肿瘤免疫疗法取得巨大进展，相比其他类型的治疗方法，免疫疗法能够提供持久的疗效，引起更少的副作用。鉴于针对PD-1/PD-L1通路的免疫治疗在不同类型肿瘤以及不同个体间的疗效存在差异，寻找能够预测PD-L1的检验方法成为研究热点。本文回顾分析了不同平台PD-L1的检测特点和临床应用，并总结了PD-L1在不同肿瘤的应答率。<br />
In recent years, tumor immunotherapy has made great progress, compared with other types of treatments, immunotherapy can provide long-lasting efficacy, causing fewer side effects. In view of the difference in the efficacy of immunotherapy for the PD-1/PD-L1 pathway in different types of tumors and between different individuals, finding a test method that can predict PD-L1 has become a research hotspot. In this paper, the detection characteristics and clinical application of PD-L1 on different platforms are reviewed and analyzed, and the response rate of PD-L1 in different tumors is summarized.
%K PD-L1，免疫组织化学技术，生物标志物，免疫治疗<br>PD-L1
%K IHC
%K Biomarker
%K Immunotherapy
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=56428