%0 Journal Article
%T 肠道菌群–大麻素系统与早泄的研究进展
Advances in the Study of Intestinal Flora-Cannabinoid System and Premature Ejaculation
%A 郑俊
%A 张俊勇
%A 张唯力
%J Advances in Clinical Medicine
%P 8330-8336
%@ 2161-8720
%D 2022
%I Hans Publishing
%R 10.12677/ACM.2022.1291200
%X 早泄是常见的性功能障碍疾病之一,选择性5-羟色胺再摄取抑制剂因提高5-羟色胺(5-hydroxytryptamine, 5-HT)浓度在治疗抑郁症时能有效延长射精潜伏时间。目前的研究指出大麻素系统与5-HT系统在功能上相互影响且相互依赖。肠道菌群能够调节机体代谢组成并以5-HT为介导最终影响个体情绪与应激,通过益生菌治疗能有效逆转肠道菌群的情绪反应。本文基于肠道菌群及大麻素系统,深入探讨肠道菌群与早泄疾病发生及治疗上的相关性。
Premature ejaculation is one of the common sexual dysfunction diseases. Selective serotonin reuptake inhibitors can effectively prolong ejaculation latency in the treatment of depression by increasing the concentration of 5-HT. Current research points to the functional interaction and in-terdependence of the cannabinoid system and the 5-HT system. Intestinal flora can regulate the body’s metabolic composition and ultimately affect individual mood and stress through 5-HT. Pro-biotic treatment can effectively reverse the emotional response of gut flora. Based on the gut micro-biota and cannabinoid system, this paper deeply explores the correlation between the gut microbi-ota and the occurrence and treatment of premature ejaculation.
%K 早泄,肠道菌群,大麻素系统,5-HT,射精潜伏时间
Premature Ejaculation
%K Intestinal Flora
%K Cannabinoid System
%K 5-HT
%K Ejaculation Latency
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=55704