%0 Journal Article %T 有机磷农药中毒的研究进展
Research Progress of Organophosphorus Poisoning %A 伊职职 %A 冯传杰 %J Advances in Clinical Medicine %P 8305-8310 %@ 2161-8720 %D 2022 %I Hans Publishing %R 10.12677/ACM.2022.1291196 %X 口服有机磷农药后需彻底洗胃,必要时需多次灌肠排出毒物;中毒后会出现烟碱样(N)及毒蕈碱样(M)症状,患者会出现腺体分泌增加及肌束震颤等症状,给予阿托品可拮抗M、N样症状;复能剂可解救尚未老化的胆碱酯酶;血液灌流可清除已入血的毒物;血液透析可清除已入血毒物产生的炎症因子;脂肪乳可将有机磷从血浆中置换出来;如出现呼吸衰竭,则需早期使用呼吸机辅助呼吸;有部分患者可能会出现相关并发症,需进一步治疗。
After oral administration of organophosphorus pesticides, gastric lavage should be done thorough-ly, and enema should be repeated to discharge the poison if necessary. After poisoning, nicotinoid and muscarinic symptoms will appear, and patients will have symptoms such as increased glandu-lar secretion and muscle bundle tremor. Administration of atropine can antagonize M and N symp-toms. The reactivator can rescue the cholinesterase before aging; Hemoperfusion removes toxins that have entered the blood; Hemodialysis can remove inflammatory factors produced by toxins in the blood; Fat emulsion can replace organophosphorus from plasma; In case of respiratory failure, early use of ventilator to assist breathing; Some patients may have related complications and need further treatment. %K 综述,有机磷中毒
Review %K Organophosphorus Poisoning %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=55698