%0 Journal Article %T Isolation and Characterization of Contaminating Bacteria from <i>Garcinia cambogia</i> Extract: Methods to Reduce Microbial Load and Its Anti-Obesity Effect in Wistar Rats %A Raj Kumar Bhosale %A Sasidharan Sakkan %A Srinivasa Murthy Venkatramanappa %A Shivaswamy Mathada Rudraiah %A Kumaraswamy Rampur %A Arulmozhi Sathiyanarayanan %A Deepa Mandlik %A Sanman Kolhe %A Sadanand Yewale %A Sriram Padmanabhan %J Natural Resources %P 147-170 %@ 2158-7086 %D 2022 %I Scientific Research Publishing %R 10.4236/nr.2022.137010 %X Objectives: This study aimed to identify the contaminating bacteria in the extract of Garcinia cambogia, which is regularly used as a dietary supplement for addressing obesity in humans. Methods: The Garcinia cambogia extract was used and experiments were conducted to isolate the contaminating bacteria and antibiotic susceptibility was tested. The organism was identified using BIOLOG system. Such an extract was used in a placebo-controlled animal study when 6 eight adult male rats weighing between 200 and 220 g were randomly distributed into three groups (n = 3) and in test group 1, a single dose of 100 mg/kg bw of Garcinia cambogia extract was given while in the test group 2, 100 mg Garcinia cambogia extract + 116 mg Picrorhiza kurroa extract were administered through oral gavage. The normal control rats were given distilled water, and the treatment lasted for 30 days. Blood plasma and liver tissues were prepared for biochemical analysis and histology studies. Results: Nearly ~10³ cfu/g of Bacillus atrophaeus was %K < %K i> %K Garcinia cambogia< %K /i> %K Hydroxy Citric Acid %K < %K i> %K Picrorhiza kurroa< %K /i> %K Liver Health %K ATP Citrate Lyase %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=119291