%0 Journal Article
%T γ-丁内酯为原料合成戊二酸的CO<sub>2</sub>光合成路径<br>CO<sub>2</sub> Photosynthetic Pathway for Synthesis of Glutaric Acid Using γ-Butyrolactone as a Raw Material
%A 梁斌
%A 谭学军
%A 丁庆华
%A 亓蒙
%A 苑梦兰
%A 李贺
%A 张千峰
%J Hans Journal of Medicinal Chemistry
%P 231-237
%@ 2331-8295
%D 2022
%I Hans Publishing
%R 10.12677/HJMCe.2022.103023
%X 研究了以γ-丁内酯为原料合成戊二酸的新路径。γ-丁内酯先通过开环生成4-溴丁酸乙酯后，再在光照条件下，以CO<sub>2</sub>为碳源进行光催化的羰基化反应，最后再水解提纯得到戊二酸，其产率为35%。反应条件温和，且所需原料简单易得。<br />
A new route to synthesize glutaric acid from γ-butyrolactone was studied. First, γ-butyrolactone is ring-opened to generate ethyl 4-bromobutyrate, and then photocatalytic carbonylation is carried out with CO<sub>2</sub> as carbon source under light conditions, and finally glutaric acid is obtained by hy-drolysis and purification. The rate is 35%. The reaction conditions are mild, and the required raw materials are simple and easy to obtain.
%K γ-丁内酯，戊二酸，4-溴丁酸乙酯，光催化，羰基化<br>γ-Butyrolactone
%K Glutaric Acid
%K Ethyl 4-Bromobutyrate
%K Photocatalytic
%K Carbonylation
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=54293