%0 Journal Article %T Operationalisation of Model for Dynamics of COVID-19 in Kenya: Trajectory of Omicron Wave in Kenya %A Shem Otoi O. Sam %A Khama Rogo %J Open Journal of Modelling and Simulation %P 314-326 %@ 2327-4026 %D 2022 %I Scientific Research Publishing %R 10.4236/ojmsi.2022.103018 %X Kenya has experienced five COVID-19 surges driven by Alpha, Beta, Delta (2x), and Omicron. These waves are accurately predicted by the OTOI-NARIMA model. Consequently, in Kenyan Lake Region Economic Bloc (LREB), private sector and NGO partnerships have been forged to strengthen regional health systems and prepare effectively for epidemic resurgence. The co-development and implementation of the so-called ¡°LREB COVID-Dx¡± digital platform enable efficient epidemic monitoring in semi-real time, referral of patients, optimal use of limited resources, and community of practice among regional health practitioners. In this paper, we describe the practical implementation of the OTOI-NARIMA model and COVID-Dx digitized platform in Kenyan COVID-19 reality, with emphasis on the latest Omicron wave. In estimating the trajectory of Omicron wave, 612 data points of daily case infections are used. The order of moving average is calculated and corresponds to reproduction number, R0. The series are normalized, superimposed, and used to derive OTOI-NARIMA model. The model is estimated and interpreted. Test statistics including Ljung-Box test, ACF, and PACF are conducted. The COVID-Dx data digitization is used to inform epidemic preparedness. The OTOI-NARIMA model in %K Omicron Trajectory %K OTOI-NARIMA %K COVID-Dx %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=118874