%0 Journal Article
%T 高光谱显微成像技术及其在病理学检测中的应用<br>Hyperspectral Microscopic Imaging Technology and Its Application in Pathological Examination
%A 王诗雨
%A 刘腾
%A 郑智德
%A 马云腾
%J Hans Journal of Biomedicine
%P 220-228
%@ 2161-8984
%D 2022
%I Hans Publishing
%R 10.12677/HJBM.2022.123027
%X 在临床实践中，病理学检测通常需要化学染色等多个繁杂步骤且成本昂贵，在术中病理检测等应用中存在极大的局限性。利用高光谱显微成像技术，不仅可对病理组织切片进行无损和快速成像，还可采集到病理组织切片丰富的光谱信息，在对高光谱显微图像进一步数据处理后，可获取关于病理组织切片的生理、生化信息，进而实现快速、准确的病理诊断。高光谱显微成像技术具有图谱合一的特点，避免了化学染色法对组织样本的伤害，不影响标本进行其它检测。本文主要介绍了高光谱显微成像技术及其发展趋势，其中着重阐述了一种新型的可编程高光谱显微成像技术及其所实现的光学染色功能，随后重点介绍了高光谱显微成像技术在病理学检测中的应用现状。<br />
In clinical practice, pathological examination usually requires many complicated steps, such as chemical staining, which is expensive and has great limitations in the application of intraoperative pathological examination. By using hyperspectral microscopic imaging technology, not only can pathological tissue sections be imaged nondestructively and quickly, but also rich spectral information of pathological tissue sections can be collected. After further data processing of hyperspectral microscopic images, physiological and biochemical information about pathological tissue sections can be obtained, and then rapid and accurate pathological diagnosis can be realized. Hyperspectral microscopic imaging technology has the characteristics of atlas integration, which avoids the damage of chemical staining to tissue samples and does not affect other detection of samples. This paper mainly introduces the hyperspectral microscopic imaging technology and its development trend, in which a new type of programmable hyperspectral microscopic imaging technology and its optical staining function are emphasized. Then, the application status of hyperspectral microscopic imaging technology in pathological examination is emphatically introduced.
%K 高光谱显微成像技术，光学染色，病理学检测<br>Hyperspectral Microscopic Imaging Technology
%K Optical Staining
%K Pathological Detection
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=53345