%0 Journal Article
%T 太子参提取物促透明质酸透皮吸收作用研究<br>Study on the Effect of <em>Pseudostellaria Heterophylla</em> Extract on Promoting the Transdermal Absorption of Hyaluronic Acid
%A 蒋畅
%A 赵立
%A 张继州
%A 阚永军
%A 胡娟
%J Hans Journal of Biomedicine
%P 206-211
%@ 2161-8984
%D 2022
%I Hans Publishing
%R 10.12677/HJBM.2022.123025
%X 目的：采用体外透皮扩散试验探究太子参提取物对透明质酸(hyaluronic acid, HA)的透皮吸收促进作用。方法：利用改良型Franz扩散池考察HA的体外经皮渗透量变化，通过单位面积累计透过量及透皮吸收系数评价太子参提取物对HA透皮吸收的促进作用。结果：在体外透皮吸收实验中，透明质酸的单位面积累计透过量随时间变化线性递增，符合零级动力学方程。与传统的透皮吸收促进剂月桂氮酮相仿，太子参提取物对HA的透皮吸收起到积极的促进作用。结论：本研究对太子参提取物促HA透皮吸收作用进行了分析探索，为太子参在功能性护肤产品中的开发利用奠定基础。<br />
Objective: Using in vitro diffusion cell method to explore the extract of <em>Pseudostellaria Heterophylla</em> to promote the absorption of hyaluronic acid (HA). Methods: Use the improved Franz diffusion cell to investigate the changes in HA’s transdermal absorption properties. Results: In the in vitro transdermal absorption experiment, the cumulative permeation amount per unit area of hyaluronic acid increased linearly with time, which conformed to the zero-order kinetic equation. Similar to the traditional transdermal absorption enhancer, lauroazone, the extract of <em>Pseudostellaria Heterophylla</em> has a positive effect on the transdermal absorption of HA. Conclusion: This study analyzed and explored the role of the extract of <em>Pseudostellaria Heterophylla</em> to the promotion of HA transparent skin, and laid the foundation for the development and utilization of <em>Pseudostellaria Heterophylla</em> in functional skin care products.
%K 太子参，透明质酸，透皮吸收<br><em>Pseudostellaria Heterophylla</em>
%K Hyaluronic Acid
%K Transdermal Absorption
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=52936