%0 Journal Article
%T 阻塞性睡眠呼吸暂停低通气综合征免疫功能的研究进展<br>Advances in the Study of Immune Function in Obstructive Sleep Apnea-Hypopnea Syndrome
%A 姜新新
%A 冯恩志
%J Advances in Clinical Medicine
%P 5627-5632
%@ 2161-8720
%D 2022
%I Hans Publishing
%R 10.12677/ACM.2022.126814
%X 阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一种呼吸性睡眠障碍，主要表现为睡眠时，上呼吸道有时被部分，有时被完全阻塞，并且反复发生的夜间打鼾，白天困倦，甚至有时出现夜间憋醒等情况，引起低通气或者呼吸暂停等症状。在低通气或呼吸暂停事件中，肺泡通气不良导致动脉血氧饱和度(SaO2)降低和二氧化碳动脉分压(PaCO2)逐渐升高，从而引起一系列并发症，如：高血压、胰岛素抵抗、冠心病等多器官、多系统损伤。此间歇性缺氧必然引起机体免疫功能及多种炎症指标发生改变，本文就OSAHS患者免疫及炎症指标做出综述，以增加对OSAHS免疫的了解，提高对OSAHS重视。<br />
Sleep apnea-hypopnea syndrome (OSAHS) is a respiratory sleep disorder, which is mainly mani-fested by partially or completely blocked upper respiratory tract during sleep, recurring nocturnal snoring, daytime sleepiness, and sometimes even nocturnal awakening, causing symptoms such as hypopnea or apnea. In hypopnea or apnea events, poor alveolar ventilation leads to decreased arte-rial oxygen saturation (SaO2) and a gradual increase in arterial partial pressure (PaCO2) of carbon dioxide, resulting in a series of complications such as hypertension, insulin resistance, coronary heart disease and other multi-organ and multi-system injuries. This intermittent hypoxia will inev-itably cause changes in the body’s immune function and a variety of inflammatory indicators. This paper reviews the immune and inflammatory indicators of OSAHS patients to increase the under-standing of OSAHS immunity and improve the attention to OSAHS.
%K 阻塞性睡眠呼吸暂停低通气，间歇性缺氧，白介素6，肿瘤坏死因子α，细胞免疫，体液免疫，
炎症指标
<br>Obstructive Sleep Apnea-Hypopnea
%K Intermittent Hypoxia
%K Interleukin 6
%K Tumor Necrosis Factor α
%K Cellular Immunity
%K Humoral Immunity
%K Inflammatory Indicators
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=52719