目的：探讨基于微信的生活方式干预对糖尿病前期患者血糖、血脂水平的影响。方法：选取2020年3月至2021年11月于杭州师范大学附属医院就诊的符合入组标准的146例糖尿病前期患者作为研究对象，按随机数字表法分为研究组和对照组，每组73例。实验组采用饮食加运动的生活方式干预，对照组给予常规治疗及健康宣教，不进行特殊干预，两组患者均干预3个月并比较两组患者干预前后的体重、身体质量指数(BMI)、腰围(WC)、空腹血糖(FBG)、餐后两小时血糖(2hPG)、糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)。结果：干预前，两组患者在各指标间的差异均无统计学意义(P > 0.05)；干预后，实验组各指标水平均低于本组干预前，对照组除BMI、L-DLC外各指标水平均低于本组干预前，差异均具有统计学意义(P < 0.05)；经组间比较，干预后实验组体重、BMI、WC、FBG、2hPG、HbA1、TG、TC、LDL-C水平均明显低于对照组，两组组间差异具有统计学意义(P < 0.05)。结论：基于微信的生活方式干预能够有效改善糖尿病前期患者的血糖、血脂水平，提高患者的自我管理能力，具有一定的应用价值。
Objective: To investigate the effects of lifestyle intervention based on WeChat on blood glucose and lipid levels in pre-diabetic patients. Methods: A total of 146 patients with pre-diabetes who met the inclusion criteria and were admitted in the Affiliated Hospital of Hangzhou Normal University from March 2020 to November 2021 were selected as the study subjects. They were divided into study group and control group by random number table method, with 73 patients in each group. The study group was given lifestyle intervention; the control group was given conventional treatment and health education with no special intervention. The intervention period was 3 months. Body mass index (BMI) , waist circumference (WC) , fasting blood glucose (FBG), 2 h postprandial blood glucose(2hPG), glycosylated hemoglobin (HbA1c), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) levels before and after intervention were compared in the two groups. Results: Before intervention, there was no statistically significant difference between the two groups in each index (P > 0.05). After intervention, the level of each index in the study group was lower than that before intervention, and the level of each index except BMI and L-DLC in the control group was lower than that before intervention, and the differences between the two groups were statistically significant (P < 0.05). After the intervention, the levels of body weight, BMI, WC, FBG, 2hPG, HbA1, TG, TC and LDL-C in the experimental group were significantly lower than those in %K 糖尿病前期，生活方式干预，微信
Prediabetes %K Lifestyle Intervention %K WeChat %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=52465