%0 Journal Article
%T 益生菌发酵蜂花粉对急性酒精中毒小鼠的解酒作用及酒精性肝损伤的保护作用<br> The Anti-Inebriation of Probiotic Fermented Pollen on Acute Alcoholism Rats and Protection on Alcoholic Liver Injury
%A 杨少波
%A 王坤
%A 李国强
%A 张付芸
%J Hans Journal of Food and Nutrition Science
%P 139-146
%@ 2166-6121
%D 2022
%I Hans Publishing
%R 10.12677/HJFNS.2022.112017
%X <div style=\"text-align:justify;\">
	<span style=\"font-size:14px;\">以急性酒精中毒小鼠为研究对象，通过测定翻正反射消失及恢复时间、脑组织中</span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-内啡肽(</span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-endomorpHin, </span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-EP)水平、血清谷丙转氨酶(</span><span style=\"font-size:14px;\">Alanine aminotransferase</span><span style=\"font-size:14px;\">, ALT)和谷草转氨(</span><span style=\"font-size:14px;\">Aspartate
aminotransferase</span><span style=\"font-size:14px;\">, AST)活性、肝脏抗氧化指标，研究益生菌发酵蜂花粉对急性酒精中毒小鼠的解酒及肝损伤的保护作用。结果表明，与模型组相比发酵蜂花粉能延长醉酒耐受时间、缩短醒酒时间，降低脑组织中</span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-EP水平，保护肝脏细胞膜的完整性，提高肝脏乙醇脱氢酶(</span><span style=\"font-size:14px;\">Alcohol
dehydrogenase</span><span style=\"font-size:14px;\">, ADH)、乙醛脱氢酶(</span><span style=\"font-size:14px;\">Aldehyde dehydrogenase</span><span style=\"font-size:14px;\">, ADLH)、超氧化物歧化酶(</span><span style=\"font-size:14px;\">Superoxide dismutase</span><span style=\"font-size:14px;\">, SOD)活性，提高还原型谷胱甘肽(Glutathione, GSH)水平、降低丙二醛(</span><span style=\"font-size:14px;\">Malonyldialdehyde</span><span style=\"font-size:14px;\">, MDA)水平。益生菌发酵蜂花粉对急性酒精中毒小鼠具有解酒作用，对酒精性肝损伤具有保护作用。</span><span style=\"font-size:14px;\"><br />
With
acute alcoholism rats as the research object, the disappearance and recovery
time of righting reflex, </span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-endomorpHin
(</span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-EP) in brain tissue, </span><span style=\"font-size:14px;\">Alanine aminotransferase</span><span style=\"font-size:14px;\"> (ALT) and </span><span style=\"font-size:14px;\">Aspartate aminotransferase</span><span style=\"font-size:14px;\"> (AST) levels,
liver antioxidant indexes were measured to explore the anti-inebriation on
acute alcoholism rats and protection on alcoholic liver injury by probiotic
fermented pollen. The results showed that compared with the model group,
probiotic fermented pollen could increase tolerance time and decrease sobering up time, reduce the level of </span><span style=\"font-size:14px;\">β</span><span style=\"font-size:14px;\">-EP in the brain tissue of rats,
protect the integrity of cell membrane in the liver, improve the activity of </span><span style=\"font-size:14px;\">Alcohol dehydrogenase</span><span style=\"font-size:14px;\"> (ADH) and </span><span style=\"font-size:14px;\">Aldehyde
dehydrogenase</span><span
%K 蜂花粉，益生菌，酒精中毒，肝损伤<br> Pollen
%K Probiotics
%K Alcoholism
%K Liver Injury
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=51323