%0 Journal Article
%T 云南省宣威地区肺癌研究进展<br>Research Progress of Lung Cancer in Xuanwei Area of Yunnan Province
%A 王慧敏
%A 陈亚娟
%J World Journal of Cancer Research
%P 67-73
%@ 2164-9057
%D 2022
%I Hans Publishing
%R 10.12677/WJCR.2022.122009
%X 肺癌严重危害着人类健康，是一个重大的公共卫生问题。位于云南省东北部的宣威地区是全球肺癌死亡率最高的地区之一。近十几年来，研究人员从不同角度探索与揭示宣威肺癌高发的原因及分子机制，从其特殊的环境因素到遗传易感性、DNA甲基化、非编码RNA等分子机制的研究都取得了显著进展。本文综述了宣威地区肺癌特点及其风险因素研究进展。<br />
Lung cancer seriously endangers human health and is a major public health problem. The Xuanwei region in northeastern Yunnan province has one of the highest lung cancer mortality rates in the world. In the past ten years, researchers have explored and revealed the causes and molecular mechanisms of the high incidence of lung cancer in Xuanwei from different perspectives. Significant progress has been made in the study of its special environmental factors to molecular mechanisms such as genetic susceptibility, DNA methylation, and noncoding RNA. This paper reviews the research progress on the characteristics and risk factors of lung cancer in Xuanwei area.
%K 地方性肺癌，易感性，DNA甲基化，非编码RNA<br>Endemic Lung Cancer
%K Susceptibility
%K DNA Methylation
%K Noncoding RNA
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=50607