%0 Journal Article
%T Synthesis and Evaluation of Quinolino-Benzoxaboroles as Potential Antimicrobial Agents
%A Greeshma P. Kumpati
%A Michael J. Williams
%A Srinidhi Mereddy
%A Joseph L. Johnson
%A Shirisha Jonnalagadda
%J International Journal of Organic Chemistry
%P 53-63
%@ 2161-4695
%D 2022
%I Scientific Research Publishing
%R 10.4236/ijoc.2022.122005
%X Several quinolino-benzoxaborole derivatives have been prepared <span style=\"font-family:Verdana;\">to </span><span style=\"font-family:Verdana;\">start</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:Verdana;\">from aminobenzoxaboroles.
These derivatives have been evaluated for their anti-</span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">cancer activity on human and murine cancer cell
lines and based on their relative non-toxicity, these compounds were further
evaluated for their antibacterial activity against </span><i><span style=\"font-family:Verdana;\">E.</span></i><span style=\"font-family:Verdana;\"> <i>coli</i></span><span style=\"font-family:Verdana;\">, </span><i><span style=\"font-family:Verdana;\">B.</span></i><span style=\"font-family:Verdana;\"> <i>subtilis</i></span><span style=\"font-family:Verdana;\">, and </span><i><span style=\"font-family:Verdana;\">M.</span></i><span style=\"font-family:Verdana;\"> <i>smegmatis</i></span><span style=\"font-family:Verdana;\">. The synthesized
compounds were also evaluated for antifungal activity in </span><i><span style=\"font-family:Verdana;\">C.</span></i><span style=\"font-family:Verdana;\"> <i>albicans</i></span><span style=\"font-family:Verdana;\"> and </span><i><span style=\"font-family:Verdana;\">C.</span></i><span style=\"font-family:Verdana;\"> <i>neoformans</i></span><span style=\"font-family:Verdana;\">.</span></span>
%K Benzoxaboroles
%K Aminobenzoxaboroles
%K Quinolino-Benzoxaboroles
%K Anti-Microbial Agents
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=116613