%0 Journal Article
%T 自由基介导的未活化烯烃的官能团向远端迁移反应研究进展<br>Recent Progress of Radical-Mediated Difunctionalization of Unactivated Alkenes through Distal Migration of Functional Groups
%A 秦一洲
%J Journal of Organic Chemistry Research
%P 1-17
%@ 2330-524X
%D 2022
%I Hans Publishing
%R 10.12677/JOCR.2022.101001
%X 自由基介导的烯烃1,2-双官能化大大拓展了烯烃的应用范围，近年来已成为热门研究领域。通常，烯烃的应用范围主要局限于活化的烯烃。然而，一类用于未活化的烯烃的官能化的通用策略已经开发出来。本文总结了分子内官能团向远端迁移的策略的最新进展，该策略已经有效地应用于自由基介导的未活化烯烃的双官能化，包括芳基，氰基，杂芳基，亚氨基，羰基，炔基和烯基在内的官能团。<br />
Radical-mediated 1,2-difunctionalization of alkenes has greatly expanded the application range of alkenes and has become a hot research area in recent years. In general, however, the scope of alkene is largely restricted to the activated alkenes. However, a general strategy for functionalization of unactivated olefins has been developed. This paper summarizes the latest progress in the strategy of distal migration of intramolecular functional groups. This strategy has been effectively applied to the bifunctionalization of non activated olefins mediated by free radicals, including aryl, cyano, heteroaryl, imino, carbonyl, alkynyl and alkenyl functional groups.
%K 自由基，未活化烯烃，官能团远程迁移<br>Radicals
%K Unactivated Alkenes
%K Remote Migration of Functional Groups
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=49667