%0 Journal Article
%T Early Life Quality on Instrumental, Daily and Neuropsychological Activities of Lewy Body Disease about 70 Patients in the Geriatric Department at the Pitié Salpêtrière Hospital of Paris, France
%A Andia Abdoulkader
%A Audrey Rouet
%A Benedicte Dieudonn¨¦
%A Jacque Boaddert
%A Charlotte Tomeo
%A Sandrine Greffard
%A Marc Verny
%J Open Journal of Internal Medicine
%P 56-68
%@ 2162-5980
%D 2022
%I Scientific Research Publishing
%R 10.4236/ojim.2022.121008
%X <strong>Background:</strong> Lewy body disease (LBD) is a neurodegenerative affection responsible for impaired quality of life. The objective was to share the data experience of 14 years concerning the functional, neuropsychological and behaviors effects on geriatrics patients. <strong>Methodology:</strong> Descriptive retrospective study over 14 years (2005 to 2019) in the geriatrics department of Piti¨¦ Salp¨¦tri¨¨re Hospital, using the <i>instrumentals activity of daily living</i> (<i>IADL</i>) sheets and the neuropsychological inventory (<i>NPI</i>) assessed at the moment diagnosis according to the diagnostic criteria of 2017 and 1996. <strong>Results:</strong> A total of 70 patients including 55 exploitable files had been listed with a mean age 82.6 years [70 - 91], a sex ratio 1.2 in men favor, a mean socio-cultural level 5.2 [1 - 7], a mean <strong>Cumulating Illness Scale</strong> (CIRS52) = 10 [1 - 22]. The mean <i>IADL</i> and <i>NPI</i> were respectively 9.3 [3 - 11] and 25.1 [0 - 79]. We found an early global impairment of <i>IADL</i> activities frequent in transport (65%), medication management (49%), and displacement (42%) for basic activities without significant statistical difference between the age and sex groups but statistically significant early involvement with polypathology after adjustment for displacement (45%) and transport (65%). The <i>IADL</i> impairment is significant as soon as the MMS-BREF decreases. Hoen Yahr (<strong>HY</strong>) scale increase could influences shopping (22%), displacement (27%) after adjustment. NPI disorders frequently found were apathy-depression (31.8% - 25%), anxiety (28%), irritability (25.6%) and sleep disturbance (22.9%) after 80 years old independently of gender and poly-pathology. Also, the best mental status was associated of less disturbance of <i>NPI</i> items. <strong>Conclusion:</strong> Polypathology, motor disorders and cognitive decline seem to influence <i>IADL</i> while with advanced age, cognitive decline appears to be worsened early in LBD.
%K LBA
%K &lt
%K i&gt
%K IADL&lt
%K /i&gt
%K &lt
%K i&gt
%K NPI&lt
%K /i&gt
%K Geriatric
%K Paris
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=115898