%0 Journal Article %T Tricky Presentation of Multisystem Inflammatory Syndrome in Children (MIS-C) with in Pediatric %A Hareth Aldosaimani %A Mayada Dawoud Khairi %A Mohammed Ayaad %J Open Journal of Pediatrics %P 196-202 %@ 2160-8776 %D 2022 %I Scientific Research Publishing %R 10.4236/ojped.2022.121021 %X Introduction: In emergence a COVID patient with multisystem inflammatory syndrome in children (MIS-C), associated with SARS-CoV-2, has shown increasing number among pediatric. Even the same presentation of Kawasaki disease we have to keep in mind MIS-C, in order to reach a consensus on this new disease in the future. Three variations of the disease patterns were reported: a group of children with increase in inflammatory activity and persistent fever, without criteria for Kawasaki disease, a second group with Kawasaki disease criteria, and a third group with shock, coronary aneurysms, severe cardiac dysfunction, and gastrointestinal symptoms. Classic Kawasaki disease is self-limited vasculitis which affects medium-sized vessels, almost occurred in children under five years old. Here, we bring a Saudi case, present to emergency department in Prince Sultan Military Medical City. Case report: 10 years old female, medically free, presented with abdominal pain, fever and skin rashes. Patient had history of COVID-19 infection 1 month before presentation. Initial investigations showed acute kidney injury with elevated inflammatory markers. Conclusion: Further evidence of the increase in the incidence of pediatric MIS-C, temporarily is associated with SARS-CoV-2. Physician should give more attentions to this new diagnosis with more fatal outcomes than Kawasaki cases. %K Kawasaki or Kawasaki-Like Syndrome %K Vasculitis %K Multi Organ Failure %K Myo-carditis %K Fever %K Abdominal Pain %K Skin Rash %K Intravenous Immunoglobulin %K Acute Kidney Injury and Raised Inflammatory Markers %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=115804