%0 Journal Article
%T Undifferentiated Arthritis Revealing CoganĄ¯s Disease
%A Paul Eloundou
%A Aly Badra Kamissoko
%A Francine Same Bebey
%A Marina Sanda
%A Al Mamy Aboubakar
%A William Nguekouo
%A Ab¨¨ni Faouziyath Yaya
%A Mireille Yomba
%A Severin Noumbissi
%J Open Journal of Rheumatology and Autoimmune Diseases
%P 29-34
%@ 2164-005X
%D 2022
%I Scientific Research Publishing
%R 10.4236/ojra.2022.121004
%X <b><span style=\"font-family:Verdana;\">Background:</span></b><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> CoganĄ¯s syndrome is a rare autoimmune vasculitis (less than </span><span style=\"font-family:Verdana;\">300 cases described in the literature)
characterized in its typical form by co</span><span style=\"font-family:Verdana;\">ch</span><span style=\"font-family:Verdana;\">leovestibular involvement, interstitial keratitis, and an inflammatory
invo</span><span style=\"font-family:Verdana;\">lvement of large vessels. It is frequently accompanied by general
signs and cardio-vascular, rheumatologic, and digestive complications. Its
management is essentially based on the use of corticosteroids and
immunosuppressants. The </span><span style=\"font-family:Verdana;\">outcome of the
treatment, even if rapid, does not always avoid functional c</span><span style=\"font-family:Verdana;\">om</span><span><span style=\"font-family:Verdana;\">plications. This disease is probably
under-diagnosed in Africa. </span><b><span style=\"font-family:Verdana;\">Objective:</span></b><span style=\"font-family:Verdana;\"> Th</span></span><span style=\"font-family:Verdana;\">e objective of this study
was to report a case of Cogan syndrome in sub-Saharan Africa. </span><b><span style=\"font-family:Verdana;\">Case</span></b> <b><span style=\"font-family:Verdana;\">report:</span></b><span style=\"font-family:Verdana;\"> A 78 year old black African female patient presented with arthritis of the left
knee without fever. The examination also revealed a bilateral deafness of
rapidly progressive onset. The patient was known to be diabetic and
hypertensive, and was regularly monitored. The biology revealed an inflammatory
syndrome and an inflammatory joint puncture fluid. Pure </span><span style=\"font-family:Verdana;\">tone audiometry confirmed a 77% hearing loss. The ophthalmological exam</span><span style=\"font-family:Verdana;\">i</span><span style=\"font-family:Verdana;\">nation revealed stromal oedema and hypertensive
retinopathy of Kendall st</span><span style=\"font-family:Verdana;\">age III. The rheumatological evolution was good
under methylprednisolone and methotrexate, but the deafness persisted. The
occurrence of a fever on day 12 </span><span style=\"font-family:Verdana;\">of treatment
required further investigations (blood culture, PCR-Covid</span></span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">19 te</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">st,
cytobacteriological
%K CoganĄ¯s Syndrome
%K Arthritis
%K Non-Syphilitic Interstitial Keratitis
%K Bilateral Deafness
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=114519