%0 Journal Article %T Rasmussen脑炎发病机制的研究现状
The Pathogenesis and Research Status of Rasmussen Encephalitis %A 刘东 %A 栾国明 %J Hans Journal of Surgery %P 1-6 %@ 2168-5576 %D 2022 %I Hans Publishing %R 10.12677/HJS.2022.111001 %X Rasmussen脑炎(Rasmussen encephalitis, RE)是一种罕见,儿童时期起病,常累及一侧大脑半球的慢性炎症性疾病,表现为难治性局灶性癫痫、部分性癫痫持续状态(epilepsia partialis continua, EPC)和进行性加重的神经功能缺损症状如偏瘫、偏盲和智力减退等。近半个世纪以来,尽管对于这种严重致残性疾病的研究不断取得重大进展,但该病的病因至今尚不明确,大脑半球离断术仍是临床治疗最重要的方法。本文就RE发病机制的研究现状做一综述,供同行参考。
Rasmussen encephalitis (RE) is a rare, childhood onset, and chronic encephalitis involving one side of the hemisphere. This disease manifested as refractory focal epilepsy, epilepsia partialis continua (EPC) and progressive neurological deficits such as hemiplegia, hemianopia and mental retardation. For nearly half a century, the significant progress of the disease has been made significant progress, but the pathogenesis of the disease is not clear, the hemispherotomy is still the most effective clinical treatment. This paper will review the pathogenesis of RE for colleague’s reference. %K Rasmussen脑炎,癫痫,发病机制,病毒感染,自身免疫
Rasmussen Encephalitis %K Pathogenesis %K Epilepsy %K Virus Infection %K Autoimmunity %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=47702