%0 Journal Article
%T Role of CD4+ and CD8+ T Lymphocyte in the Onset of Stroke in People Living with HIV in Pointe-Noire
%A Prince Eliot Galieni Sounga Bandzouzi
%A Ghislain Armel Mpandzou
%A Josu¨¦ Euberma Diatewa
%A Dina Happia Motoula-Latou
%A Charles Godefroy Koubemba
%A Paul Macaire Ossou-Nguiet
%A Donatien Moukassa
%J World Journal of Neuroscience
%P 1-7
%@ 2162-2019
%D 2022
%I Scientific Research Publishing
%R 10.4236/wjns.2022.121001
%X <strong>Objective:</strong><span><span style=\"font-family:;\" \"=\"\"> To determine the role of CD4+ and CD8+ T
lymphocytes in the onset of stroke in people living with HIV. <b>Methodology:</b> This was a descriptive, cross-sectional study from January to July 2019, in the
neurology department of loandjili general hospital, including any patient
hospitalized for a first episode of stroke confirmed by brain scan. The study
variables were: age, sex, CRP value, serum T cell CD4+, CD8+. The statistical
analysis was carried out using the EPI info 7 software. <b>Results:</b> Twenty
stroke patients were included. The relative frequency of HIV was 20%. The risk
factors were potent<span>iated by immunosuppression
of CD4+ T cells. Sixty percent (60%) of the patients had a CD4+ count &lt;
200/mm<sup>3</sup> and the mean CD4+ count was</span> <span>ˇŔ191/mm<sup>3</sup>. Stroke was the predominant mechanism of injury with
a fre</span>quency of 70%, the only injury mechanism of stroke in patients with
CD8+ T cell count &gt; 800/mm<sup>3</sup> (p = 0.04). <b>Conclusion:</b> Risk factors
are potentiated by TCD4+ lymphocyte immunosupression, also CD8+ lymphocytes of
immune <span>system activation marker are a cardiovascular
risk factor for living people</span> with HIV.</span></span>
%K CD4+
%K CD8+ T Lymphocytes
%K HIV
%K Stroke
%K Pointe-Noire
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=114423