%0 Journal Article
%T Does the Location and Prevelance of Gastric Intestinal Metaplasia Change in Patients with Functional Dyspepsia
%A Tahir Buran
%A Elmas Kasap
%A Semin Ayhan
%J Open Access Library Journal
%V 8
%N 12
%P 1-9
%@ 2333-9721
%D 2021
%I Open Access Library
%R 10.4236/oalib.1107982
%X Gastric intestinal metaplasia plays a significant role in the pathogenesis of intestinal gastric cancer. Objective: A retrospective analysis of demographic characteristics, site of involvement, and incidence was performed involving patients who underwent endoscopy who had biopsy-diagnosed intestinal metaplasia. Materials and Methods: The study included 720 patients with functional dyspepsia retrospectively from among 6160 patients who underwent upper endoscopy in Celal Bayar University, Faculty of Medicine, Gastroenterology Department, between 2014 and 2020. Results: Intestinal metaplasia was detected at the antrum, corpus, and angulus in 59.94%, 13.47%, and 28.57% of the cases, respectively. Antral lesions were significantly more prevalent (P < 0.05). Of the patients with IM, 63.5% had HP positivity, with a significant association between IM positivity and HP positivity (P < 0.05). There was a significant difference between patients with or without a history of chronic PPI use in terms of the prevalence of intestinal metaplasia (P < 0.05). Conclusion: These results suggest that the endoscopic follow-up of patients with IM requires additional attention to the lesser curvature of the antrum as well as the gastric angulus.
%K Gastric Intestinal Metaplasia
%K Helicobacter Pylori
%K Gastritis
%K Functional Dispepsia
%U http://www.oalib.com/paper/6763874