%0 Journal Article %T Health Indicator Bacteria That Is Useful for Risk Assessment of Peri-Implantitis %A Hidenori Suzuki %A Osamu Tsuzukibashi %A Akira Fukatsu %J Open Journal of Stomatology %P 360-372 %@ 2160-8717 %D 2021 %I Scientific Research Publishing %R 10.4236/ojst.2021.119032 %X We established a novel identification method for oral Rothia species using one-step multiplex PCR analysis to investigate whether the monitoring of oral Rothia species levels is useful for peri-implantitis risk assessment, and to examine the oxygen concentration that these organisms need for growth in vitro. The mean number and proportion of Rothia aeria in peri-implant sulcus fluid (PISF) samples was significantly higher in the healthy implant group than in the peri-implantitis group (P < 0.05). Moreover, R. aeria under aerobic conditions vigorously grew compared with those under anaerobic conditions, and this organism grew only at the upper layer where high oxygen concentrations existed in a semi-liquid nutrient medium. Therefore, the monitoring of R. aeria levels may be suitable as an indicator of healthy peri-implant tissue conditions for the prevention of peri-implantitis. %K Peri-Implantitis %K Multiplex PCR %K < %K i> %K Rothia aeria< %K /i> %K Oral Cavity %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=112033