%0 Journal Article
%T 植物多糖抗炎作用及机理研究进展<br>Progress on Anti-Inflammatory Effects and Mechanisms of Plant Polysaccharides
%A 陆可安
%A 付婉妹
%A 奚雨佳
%A 黄敏萱
%A 丁志山
%J Open Journal of Nature Science
%P 384-390
%@ 2330-1732
%D 2021
%I Hans Publishing
%R 10.12677/OJNS.2021.94043
%X 植物多糖作为一种同时具备多种生物活性的天然产物，因其多靶点、低毒等特点已经成为了抗炎药物治疗领域的研究重点。本文对近年来植物多糖抗炎作用的研究加以综述，从植物多糖对炎症相关细胞因子、iNOS和COX-2、NF-κB相关信号通路等方面的影响阐述其抗炎机理，并讨论植物多糖结构与抗炎药理活性的关系，对植物多糖未来研究的发展趋势做出展望，以期为抗炎药物的研发提供理论基础。<br />
As a natural product with multiple biological activities, plant polysaccharides have become the focus of research in the field of anti-inflammatory drug therapy because of their high efficiency and low toxicity. This paper summarizes the study of anti-inflammatory effect of plant polysaccharides in recent years, and lays high emphasis on the effect of polysaccharide to inflammatory cytokines, iNOS and COX-2, the NF-κB pathway and so on, which could be the possible anti-inflammatory mechanisms, and discuss the relationship between the polysaccharide structure and anti-inflammatory pharmacological activities. In addition, it prospects about the development trend of future research of plant polysaccharide, in order to provide a theoretical basis for the re-search and development of anti-inflammatory drugs.
%K 植物多糖，抗炎，作用机制<br>Plant Polysaccharides
%K Anti-Inflammatory
%K Mechanism
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=43616