%0 Journal Article
%T Feasibility of Complete Cytoreduction in Advanced Epithelial Ovarian Cancer
%A Noha E. Hassan
%A Abdel Fattah Agameya
%A Amal Alsonoussi
%A Mahmoud Meleis
%J Open Journal of Obstetrics and Gynecology
%P 836-844
%@ 2160-8806
%D 2021
%I Scientific Research Publishing
%R 10.4236/ojog.2021.117078
%X <strong>Objective:</strong><span style=\"font-family:Verdana;\"> Complete resectability of all visualized tumor
implants at debulking surgery for advanced epithelial ovarian cancer is
confirmed to be the s</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">ingle most important prognostic factor. This study
aims</span><b> </b><span style=\"font-family:Verdana;\">to develop </span><span style=\"font-family:Verdana;\">preoperative</span><span style=\"font-family:Verdana;\"> predicting score based on clinical, biological, and radiological criteria of
epithelial ovarian cancer to assess the feasibility of complete cytoreduction. </span><b><span style=\"font-family:Verdana;\">Study
Design: </span></b><span style=\"font-family:Verdana;\">A retrospective record-based study. </span><b><span style=\"font-family:Verdana;\">Patients and Methods: </span></b><span style=\"font-family:Verdana;\">The
study was conducted upon 50 consecutive patients managed for epithelial ovarian
cancer with FIGO stage III. Patients¡¯ data were collected from records of the
Gyne-Oncology Clinic of El Shatby University Maternity Hospital affiliated </span><span style=\"font-family:Verdana;\">to</span><span style=\"font-family:Verdana;\"> Alexandria University. </span><b><span style=\"font-family:Verdana;\">Results:</span></b></span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">Many parameters were significantly associated with completeness of
resectability in univariate analysis; including age, BMI, CA125, albumin,
pre-albumin, PCI, mesenteric, and right copula of diaphragm affection by CT
scan (</span><span style=\"font-family:Verdana;\">p value</span><span style=\"font-family:Verdana;\"> &lt; 0</span></span><span style=\"font-family:Verdana;\">.</span><span style=\"font-family:Verdana;\">05). A 100-point
predictability score was developed, 10 for BMI ¡İ</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">35 kg/m</span><sup><span style=\"font-family:Verdana;\">2</span></sup><span style=\"font-family:Verdana;\">, 25 </span><span style=\"font-family:Verdana;\">point</span></span><span style=\"font-family:Verdana;\">s</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> for Pre albumin &lt; 14.5 mg/dl, 35 </span><span style=\"font-family:Verdana;\">point</span></span><span style=\"font-family:Verdana;\">s</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> for
mesenteric
%K Cytoreduction
%K Ovarian Carcinoma
%K Predictive Score
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=110449