%0 Journal Article
%T <i>¦Â</i>-HCG Level as a Predictive Marker of Pregnancy Progression or Retrogression
%A George Gborienemi Simeon
%A Marymar Ezejimofor
%A Newton Cleston Odumoson
%J Open Journal of Obstetrics and Gynecology
%P 713-719
%@ 2160-8806
%D 2021
%I Scientific Research Publishing
%R 10.4236/ojog.2021.116066
%X An ordered sequence of biologic events is precursors of the birth of a
healthy baby. Hormonal interactions acting as a nexus between the fetus,
placenta and mother that controls the establishment and progression of
pregnancy and fetal development are very important. We examined the role of
Beta-Human Chorionic Gonadotropin (¦Â-HCG)
as a predictive marker. Applying radioimmunoassay that utilizes anti-sera
generated from specific ¦Â-submit of
HCG we evaluated the serum ¦Â-HCG
level in 60 pregnant women in the three trimesters. Results showed that there
was consistent increase in concentration that drops gradually and maintained a
plateau only to drop from the 40th week of pregnancy. 3 subjects
(5%) that had a sudden sharp drop in ¦Â-HCG
level resulted in complications. Inclusion of ¦Â-HCG level screening and monitoring in pregnancy will raise
assurance of progress or retrogression in pregnancy. We provide data that can
be used as a reference range for ¦Â-HCG
using this method.
%K <
%K i>
%K ¦Â<
%K /i>
%K -HCG
%K Predictive
%K Marker
%K Pregnancy
%K Progression
%K Retrogression
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=109828