%0 Journal Article %T Antioxidant Activity of Hydro-Acetonic, Hydro-Methanolic and Aqueous Leaf and Bark Extracts of <i>Sclerocaria birrea</i> (A. Rich.) Hochst %A Lahat Niang %A Seid Ali Mahamat %A Nicolas Cyrille Ayessou %A Mady Cisse %A Codou Mar Diop %J Food and Nutrition Sciences %P 429-438 %@ 2157-9458 %D 2021 %I Scientific Research Publishing %R 10.4236/fns.2021.125033 %X Bioactive compounds in plants are associated with the reduction of chronic diseases. The free radical scavenging activity of different extracts of a medicinal plant, <i>Sclerocarya birrea</i>, has been investigated using the DPPH test, ABTS test and FRAP. Three extracts were prepared from the leaves and bark: hydro-methanolic, hydro-acetonic and aqueous. Phytochemical screening was carried out the standard methods followed by the determination of the polyphenol by Folin-Ciocalteu method. The analysis of variance (ANOVA) with the STATISTICA 7.1 and statistical significance was set at p < 0.05. Evolution of percent inhibition (PI) as well as the IC50 of the extracts was obtained using the Origin Pro 8.5 software and Microsoft Excel. The results show that the bark extracts are about twice as rich in polyphenols as the leaves. With DPPH at 1.25 mg/mL, the bark has a PI of 91.04% ¡À 0.001% while leaves, reach 99.80% ¡À 0.021%. As for the ABTS test, the bark extract reached its maximum activity at 1.25 mg/mL with a PI of 99.80% ¡À 0.003% while leaves extract %K < %K i> %K Sclerocarya birrea< %K /i> %K Antioxidant Activity %K DPPH %K ABTS %K Total Phenolic %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=109012