%0 Journal Article
%T Dysplastic Gangliocytoma: A Rare Example of Cerebellar Tumor with An Evident Genetic Profile (Cowden Syndrome)
%A Javier Ortiz Rodr¨ªguez-Parets
%A Luis Miguel Chinchilla T¨¢bora
%A Enrique Montero Mateos
%A Elisa Mu£¿oz Torres
%A Mar¨ªa Dolores Lude£¿a de la Cruz
%J Open Journal of Pathology
%P 33-37
%@ 2164-6783
%D 2021
%I Scientific Research Publishing
%R 10.4236/ojpathology.2021.112004
%X <div style=\"text-align:justify;\">
	<span style=\"font-family:Verdana;\"><strong>Objective:</strong> To describe the histological and immunohistochemical findings observed when studying a dysplastic cerebellar gangliocytoma observed in a 33-year-old man with a history of Thyroid Cancer. <strong>Material and Methods:</strong> Radiological images (MRI) and histological and immunohistochemical preparations obtained from the cerebellar tissue were received in our laboratory. <strong>Results:</strong> A neoplasm constituted by aberrant-looking mature neurons was observed that showed negativity for the immunohistochemical markers of the PTEN protein, expression of the activity of the PTEN gene. <strong>Conclusions:</strong> Verify the diagnosis of a rare entity, clearly related in scientific publications with Cowden¡¯s Syndrome.</span>
</div>
%K Dysplastic Gangliocytoma
%K Immunohistochemistry
%K Cowden Syndrome
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=108699