%0 Journal Article
%T 抗生素替代疗法：噬菌体疗法<br>Antibiotic Replacement Therapy: Phage Therapy
%A 向宇波
%A 周逸仙
%A 艾沁悦
%A 石廷玉
%J Advances in Microbiology
%P 30-42
%@ 2327-0829
%D 2021
%I Hans Publishing
%R 10.12677/AMB.2021.101005
%X <div style=\"text-align:justify;\">
	近年来由于抗生素的滥用，细菌耐药已成为当前临床感染治疗面临的严峻问题，为解决细菌耐药的问题，科学家们再次把目光转移到被人们质疑甚至遗忘的噬菌体疗法上。噬菌体疗法通过噬菌体这种特殊的病毒及其衍生物可以裂解细菌治疗病原菌感染。噬菌体疗法在细菌耐药性日益严重的今天展现出了其独特的抗菌优势，是目前治疗细菌性感染特别是耐药菌的研究热点。本文对传统的常规噬菌体疗法以及以常规噬菌体疗法为基础演变而来的各种疗法进行了介绍，并分析了他们的优势和缺陷。<br />
In recent years, due to the abuse of antibiotics, bacterial resistance has become a serious problem in the treatment of clinical infection. In order to solve the problem of bacterial resistance, scientists once again turn their attention to the phage therapy which has been questioned or even forgotten by people. Phage therapy treats bacterial infections by using bacteria from this specific virus and its derivatives. Phage therapy has shown its unique antibacterial advantages in today’s increasingly serious bacterial resistance, and it is currently a research hotspot in the treatment of bacterial infections, especially drug-resistant bacteria. In this paper, we introduce the traditional conventional phage therapy and the various therapies that have evolved on the basis of conventional phage therapy, and analyze their advantages and disadvantages.
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%K 噬菌体，细菌耐药性，噬菌体疗法，裂解酶，基因工程<br>Phage
%K Bacterial Resistance
%K Phage Therapy
%K Lysase
%K Genetic Engineering
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=40900