%0 Journal Article
%T C-reactive protein and red cell distribution width as indicators of complications in patients with acute appendicitis
%A Okan Murat Akt¨¹rk
%J -
%D 2019
%X Aim: Acute appendicitis is one of the most common operations in general surgery. When complicated, mortality and morbidity increases. We aimed to find out whether use of C-reactive protein (CRP) and red cell distribution width (RDW) may help to find out development of complications with acute appendicitis at initial evaluation in an emergency department. Methods: Files of the patients who underwent operations for acute appendicitis between January 2017 and August 2017 were reviewed. Development of complications was recorded and the patients were grouped as with and without complications and were compared about age, sex RDW, CRP, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Diagnostic efficiency of CRP and RDW on the development of complications in acute appendicitis was investigated with regression analysis and by receiver operator characteristic curve analysis. Results: Age, CRP and RDW were found to be significantly related to perforation (p<0.001 for all) (Bonferoni correction), while white blood cell (WBC), AST and ALT were found to be insignificant (p=0.052, p=0.806 and p=0.804, respectively. There was a significant correlation between RDW and CRP in the Spearman non-parametric correlation analysis (correlation coefficient r=0.244 and p<0.001). There was no significant correlation of WBC to CRP and RDW. Conclusion: CRP and RDW are biochemical parameters that help us to identify the development of complications in acute appencitis. CRP may be elevated in acute appendicitis; however, it must be kept in mind to be cautious about a potentially complicated acute appendicitis after a certain level, RDW in our study has been found to be elevated in complicated appendicitis cases; but, it may not helpful to detect for perforated or gangrenous appendicitis
%K akut apendisit
%K hematolojik testler
%K laboratuar analiz
%K komplikasyonlar
%U http://dergipark.org.tr/acem/issue/47515/546308