%0 Journal Article
%T Analysis of Vitamin D Receptor Fok1 (rs2228570) and Bsm1 (rs1544410) Polymorphism in Turkish Athletes
%A Basak Funda EKEN
%A Canan SERCAN
%A Deniz KIRA£¿
%A Hazal GEZM£¿£¿
%A Korkut ULUCAN
%A Serap AKY¨¹Z
%A Sezgin KAPICI
%J -
%D 2018
%X Aim: Vitamin D is an important molecule responsible for the development, contraction and regeneration of muscles. In this study, we aimed to research the distribution of vitamin D receptor (VDR) Fok1 (rs 2228570) and Bsm1 (rs1544410) polymorphisms in professional Turkish athletes. Method: A total 27 athletes including 13 female and 14 male athletes participated in the study. Following DNA isolation, polymorphisms of VDR were determined by real-time PCR (RT-PCR). Findings: 12 of the athletes have CC, 5 of them have CT and 10 of them have TT genotypes in terms of Fok1 polymorphism. 6 female athletes were determined as CC, 2 of them as CT and 5 of them as TT genotype. 6 male athletes were found as CC, 3 of them as CT and 5 of them as TT genotype. For Bsm1 polymorphism, 9 athletes have AA, 14 of athletes have AG and 4 of them have GG genotypes. 3 of the female athletes have AA, 8 of them have AG and 2 of them have GG genotypes. 6 of male athletes have AA, 6 of them have AG and 2 of them have GG genotypes. Conclusion: In our study, it was observed that CC genotype and C allele for Fok1 polymorphism were dominant of AG genotype and A allele in Bsm 1. We believe that this study will be a reference for new studies to research the effect of VDR gene on athletic performance
%K D vitamini resept£¿r¨¹
%K sporcular
%K spor geneti£¿i
%K polimorfizm
%U http://dergipark.org.tr/igusabder/issue/41940/453412