%0 Journal Article
%T Evaluation of Blood Thyroid Hormone Level in Ceramic Workers Diagnosed with Silicosis
%A Mevl¨¹t KARATA£¿
%J -
%D 2019
%X Abstract Background: In this study, it was aimed to evaluate the thyroid hormone levels of ceramic workers with silicosis and ceramic workers without silicosis. Methods: 260 cases (134 controls) who were employed in the ceramic industry and who applied to Ankara Occupational and Enviromental Diseases Hospital to be examined were included in the study. Laboratory data, radiological reports, demographic characteristics, smoking history and detailed work history were retrospectively reviewed and recorded from patient files. Results: The mean age of the silicosis group was 38.6¡À6.7 years and the mean age of the control group was 35.2¡À5.6. The working period of silicosis group was 12 years (1-25) and the control group was 9 years (2-32). The duration of smoking in the silicosis group was 10 years (0-30) and in the control group 7 years (0-30). A significant difference was found between age, duration of study and duration of smoking in both groups, and p value was respectively (p=0.001, p <0.00, p=0.018). FEV1pred, FVCpred, and FEV1/FVC ratios were lower in the silicosis group compared to the control group but these values were not statistically different. In the silicosis group sT3=2.99¡À0.33 pg/ml, sT4=0.88 pg/ml (0.67-0.94), TSH=1.28 mcIU/ml (0.15-6.24), sT3/sT4=3.51¡À0.51 were found to be lower than the control group. A significant difference was found between sT3 and sT4 levels in silicosis and control groups (p<0.001, p=0.045). Conclusion: In this study, sT3 and sT4 were significantly lower in the patients with silicosis than in the control group. Possible thyroid hormone disorders should be considered in routine clinical diagnosis processes of patients with silicosis
%K Silikozis
%K Seramik i£¿£¿isi
%K Pn£¿mokonyoz
%K Serbest T3
%K Serbest T4
%U http://dergipark.org.tr/hutfd/issue/44085/478184