%0 Journal Article
%T The Biological Significance of Bacterial Biofilms and Effective Control Strategies
%A Demet HAN£¿ER AYDEM£¿R
%J -
%D 2018
%X Bacteria can adhere to inanimate surfaces, such as prostheses, permanent medical devices, as far as living surfaces, and can form a biofilm composed of extracellular polysaccharides, proteins, and other components. Bacteria growing in the biofilm are resistant to many antibiotic effects and the innate immune system. Biofilm formation may increase resistance to antimicrobials in the host, as well as induce inflammatory reactions, leading to persistent infections due to chronic inflammation. More than 60% of all microbial infections are estimated to be due to biofilms. Especially, if clinicians are made more aware of the importance of the bacterial biofilm formation and associated diseases, more research and new treatment approaches can be developed. However, attempts have been made to develop effective strategies to counteract the harmful effects of biofilms, and further research is needed to design appropriate therapies for the destruction of microbial biofilms. In this review, it is aimed to summarize the biological significance of bacterial biofilms and the promising effective control strategies for the control and treatment of bacterial infections
%K Bakteriyal biyofilm
%K biyofilm direnci
%K quorum sensing
%K antibiyofilm stratejiler
%U http://dergipark.org.tr/tjls/issue/38007/395099