%0 Journal Article %T Clinical and Radiological Significance of Transient Brain Lesion in the Corpus Callosum Splenium: 2 Case Reports %A Fettah Eren %J - %D 2018 %X Although rare, splenium of the corpus callosum (SCC) may be involved in many etiological conditions. Most forms of involvement are permanent and minorities of these are transient. The pathophysiology is intra-myelinic axonal edema related to hyponatremia and local inflammatory cell infiltration. The first case; 34-years-old female patient accepted to our unit with recurrent complex-partial seizures. She had epilepsy for 10 years and carbamazepine using for 4 years. Second case; 22-years-old female patient presented with vomiting, nausea and visual deficiency. Both cases magnetic resonance imaging (MRI) showed focal diffusion limitation in SCC. A comprehensive diagnostic work-up was carried out to account for these clinical and neuro-radiological presentations. 1-month follow up MRI showed resolution of these lesions. Previously, transient limitation of diffusion of SCC has been mostly reported in epileptic patients and treatment with anti-epileptic agents. However, many other conditions may result the appearance of similar clinical states. These patients may have mild form of encephalopathy and the prognosis is generally good. MRI is particularly sensitive in early identification of these lesions. A good understanding of the transient nature of the condition may allow avoidance from unnecessary invasive diagnostic and therapeutic methods %K korpus kallozum %K splenium %K ge£¿ici lezyon %K manyetik rezonans g£¿r¨¹nt¨¹leme %U http://dergipark.org.tr/kaftbd/issue/38947/544667