%0 Journal Article
%T Paraoxonase 1 and Arylesterase Levels in Patients with Ulcerative Colitis and Their Relationships with the Disease Activity
%A Mustafa Kaplan
%J -
%D 2019
%X Background and Aims: In this study, we studied serum paraoxanase 1 and arylesterase levels in patients with ulcerative colitis and their relationship with disease activity. Material and Methods: Thirty-eight patients with active ulcerative colitis and 38 healthy controls were included in this study. Paraoxanase 1 and arylesterase enzyme activities in both active and remission phases were studied. Paraoxanase 1 and arylesterase enzyme activities in the active disease phase, the remission phase, and the control group were compared. Results: The mean patient age in the study group was 40.3¡À14.6 years (19-78); 20 patients were male (52.6%) and 18 were female (47.4%). The demographic characteristics of the patients in the control group were similar to those of the study group. The mean serum paraoxanase 1 level was 65.8¡À15.0 U/L, and the mean serum arylesterase level was 151.0¡À236.6 U/mL in patients in the active phase. The mean serum paraoxanase 1 level was 82.4¡À58.4 U/L, and the mean serum arylesterase level was 94.1¡À134.6 U/mL in patients in the remission phase. The mean serum paraoxanase 1 level was 131.7¡À63.5 U/L, and the mean serum arylesterase level was 287.3¡À295.6 U/mL in the control group. There was no statistically significant difference in mean paraoxanase 1 and arylesterase levels between patients in the active and remission phases (p > 0.05). The mean levels of paraoxanase 1 and arylesterase in patients in the active and remission phases were significantly lower than those in healthy controls (p < 0.05). Conclusion: In patients with ulcerative colitis, paraoxanase 1 and arylesterase enzyme activities were found to be significantly lower than those in the control group, but there was no relationship between disease activity and paraoxanase 1 and arylesterase enzyme activities
%K Paraoksonaz 1
%K inflamatuvar barsak hastal£¿£¿£¿
%K ¨¹lseratif kolit
%U http://dergipark.org.tr/agd/issue/45511/543505