%0 Journal Article %T Etiological evaluation of the extremely elevated erythrocyte sedimentation rate in adults %A Bet¨¹l Eri£¿mi£¿ %J - %D 2019 %X Aim: Erythrocyte sedimentation rate (ESR) is a simple and inexpensive laboratory test that is often desired in clinical practice. Normal range of ESR; 2-5 mm in men, 7 mm in women, in the first hour and 9 mm in men,12 mm in women in the second hour. Excessive elevation of ESR (¡Ý 100 mm/h) is often associated with serious diseases. Material and Method: Records of patients who applied to University of Health Sciences Dr. Sadi Konuk Education and Research Hospital internal medicine outpatient clinics, in 2016-2018 years, with an ESR value of 100 mm/hour were reviewed retrospectively. The age, sex, hemogram, biochemistry and diagnosis of these patients were recorded. For each variable considered in the study, normality tests were performed, and Kolmogorov-Smirnov and Shapiro-Wilk tests were applied. Mann-Whitney-U test was used for 2 groups, Kruskal-Wallis test was used for 3 groups and above. Analyzes were made with SPSS 22.0 version and the significance level was taken as 0.05. Results: A total of 397 patients, 160 male and 237 female were included in the study. The Median ESR value was 113 mm/hour. Patients were divided into five diagnostic categories: infection (18.6%), malignancy (25.1%), inflammatory/connective tissue diseases (9.5%), renal diseases (12%) and other causes (34.5%). In cases where etiology was found, most frequent cause was malignancy in females and infection in male patients. Conclusion: However, since the most common etiologic factors in the persistence of high ESR are malignancy and infection, it will be helpful first to screen patients from these angles %K malignite %K enfeksiyon %K eritrosit sedimentasyon h£¿z£¿ %U http://dergipark.org.tr/ortadogutipdergisi/issue/45182/427550